The normal dose for evening primrose oil is 1000mg to 3000mg/day. It is also used for Alzheimer’s disease, arthritis and heart disease, according to … Generally speaking, a daily dose of 500 milligrams is considered safe in adults, although many can tolerate up to 1,300 milligrams daily without any side effects. Meta-analyses conducted with 7 studies using participant-reported improvements (n = 176) and 8 using physician-assessed improvements (n = 289) support previous reports of the lack of effectiveness of evening primrose oil.67, While an older review suggested promising results12 the most comprehensive meta-analysis to date did not establish efficacy.10 Clinical studies continue to be conducted, with a gradual time-dependent improvement suggested.13, There is no recent evidence to support older studies38, 39, 40 suggesting that evening primrose oil reduced platelet aggregation. Take 3,000 mg daily for the first 12 weeks to rebuild GLA stores and then 1,000 mg as a maintenance dose. Always take evening primrose supplements with your meal. Although proponents claim that this oil may help with conditions such as eczema, dry eye, chronic pain, and women’s hormonal issues, there is insufficient evidence to support most uses. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. Bleeding may occur. For rheumatoid arthritis take 540 mg (one capsule of 500mg) daily to 2800mg (5-6 capsules of 500mg) daily in divided doses. 1,3 Today, this oil is commonly used as a carrier oil for essential oils but carries its own benefits, as well. Most of these side effects can be avoided by starting the treatment in … As a dietary supplement, there are no universal guidelines directing the appropriate use of evening primrose oil. This oil is also good for other inflammatory conditions of the skin, such as psoriasis and eczema, and can protect wounds and cuts from infection. aging. Our range makes it easy to select the best omega oil product to support your body from the inside out. Minimize Breast Pain. F… You should talk with your health care provider for complete information about the risks and benefits of using this product. Evening primrose oil has been administered orally in clinical trials at doses between 1 and 8 g/day in adults and 2 and 4 g/day in children. Take 500 mg two times a day. And the 1300mg content of GLA will cover your daily need with 2 capsules only. Topical application of evening primrose oil is used to relieve pain, but its efficacy for nerve pain has not been ascertained. The recommended dose is 500mg of evening primrose oil capsule daily or 360 mg to 480 mg GLA from evening primrose oil daily for six months. Starting at 35 weeks take 1 capsule (500 mg) of evening primrose oil orally. Both linoleic and GLA are normally present in breast milk, and it is reasonable to assume that evening primrose oil may be taken while breast-feeding. This oil has a number of medicinal uses and hence, is widely used in the management of several disorders. twice daily. This oil contains a fatty acid called gamma-linolenic acid, or GLA for short, as well as linoleic acid. – Different conditions require different dosages. Mild self-limiting nausea was reported in 2 women in the intervention group.68. Evening primrose oil to induce labor: when to start? ... What is evening primrose oil? Contents of evening primrose oil per capsule may be different for different brands. Wild varieties of O. biennis contain highly variable amounts of linoleic acid and GLA; however, extensive crossbreeding has produced a commercial variety that consistently yields oil with 72% cis-linoleic acid and 9% GLA.2, 3 Also found are cis-6,9,12-octadecatrienoic acid; small amounts of oleic, palmitic, and stearic acids; steroids; campesterol; and beta-sitosterol. So 500mg twice a day or three times a day. Evening primrose oil (EPO) is among the best treatments that can be used to relieve menopause symptoms. READ >>> Evening primrose oil for menopause – reviews, dosage, and effects. We comply with the HONcode standard for trustworthy health information -. Evening Primrose Oil Dosage may vary from 500 mg to 3000mg depending on the health condition. When Buying: Look for high-quality evening primrose oil certified as organic by a reputable third party. What Are The Best Essential Oils For Nail Fungus? If you’re approaching menopause or have already entered menopause, you might be concerned about some of the symptoms, such as hot flashes and difficulty sleeping. Therefore, always pay attention to the information on the label regarding the oil content. A more recent randomized, controlled trial found no effect on endothelial function or vascular tone with evening primrose oil supplementation.42, A review of 3 randomized, controlled trials suggested evening primrose oil might improve symptoms of diabetic neuropathy. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Also known as "king's cure-all" or "night willow herb," evening primrose is a wildflower with medicinal properties. To moisturise skin or hair, you’ll want to use oil – or a product containing the oil – directly on your skin/hair. Evening primrose oil increases the speed with which triglycerides decompose into glycerol and fatty acids. Evening primrose oil dosage for rheumatoid arthritis. Warnings. Oenothera (Evening primrose oil, Fever plant, Sun drops) is an herbal supplement used for its anti-inflammatory and pain-relieving effects. The dose is calculated on the basis of a clinical study [1]. Side effects, drug interactions, dosage, storage, and safety information should be reviewed prior to taking this supplement. As a rule, medical studies estimate dosage of EPO based on the severity of inflammation. The recommended evening primrose oil dosage is 1-6 capsules a day, at a dose of 500 milligrams per capsule. Suitable dosage of evening primrose oil depends on many factors. Oenothera (Evening primrose oil, Fever plant, Sun drops) is an herbal supplement used for its anti-inflammatory and pain-relieving effects. There is no official upper limit for EPO, but the European Medicines Agency warns that children under 12 should not take it.17 You should also avoid taking EPO if you:18 1. are on blood thinning drugs like warfarin, as EPO has blood-thinning effects 2. are due to have surgery in two weeks 3. have epilepsy, s… Several studies have shown, that supplements with gamma-linolenic acid can reduce both inflammatory and non-inflammatory acne lesions. Capsules and tablets typically contain 500 mg evening primrose oil [ 31 ]. Some conditions may be benefitted with a small dosage, like 350 mg per day. Evening primrose oil is a herbal supplement that comes from the evening primrose plant. We use cookies to ensure that we give you the best experience on our website. Side Effects of Evening Primrose Oil. Side effects of supplementing with evening primrose oil include headaches and mild stomach upset (diarrhoea or nausea). Evening primrose oil acne dosage equals to 1000mg daily. Usually, the higher the content of EPO shown on the bottle, the larger will be the capsule. With high amounts of natural omega-6 fatty acids, linoleic acid, and gamma-linolenic acid (GLA), evening primrose oil inhibits the body's natural production of the chemicals which generally cause inflammation on the skin as well as in the joints. Standard dosage varies according to … This information should not be used to decide whether or not to take this product. Disclaimer: None of the statements made on this website have been reviewed by the Food and Drug Administration. The 1300mg capsule would be even bigger than the 1000mg capsule of evening primrose oil. They include nausea, headache, stomach, pain and loose stools. Evening primrose oil has been administered orally in clinical trials at doses between 6 and 8 g/day in adults and 2 and 4 g/day in children. Always consult your doctor before use and start with a low dose. A trend toward reduction of morning stiffness and joint tenderness, as well as pain relief, has been shown. Evening Primrose Oil Side Effects. Evening Primrose Oil. It is an oil obtained from the seeds of evening primrose. Studies conducted in children with dyslexia suggest improved reading, spelling, and behavior45, 46 while a Cochrane systematic review and a long-term study (39 months) showed no long-term benefit in infants fed formula supplemented with long-chain polyunsaturated fatty acids.47, 48 An open study found benefit with the use of a fish oil and evening primrose oil combination in children with dyslexia.49, Study results disagree as to the effect of evening primrose oil on dry eye syndrome37, 50, 51 and there is concern regarding high intake of linoleic and linolenic acid and the risk of cataract development.52, 53, A prospective, double-blind, randomized placebo-controlled trial in 60 Iranian women with gestational diabetes mellitus investigated the effect of vitamin D3 (1,000 units) plus evening primrose oil (1,000 mg) on insulin resistance and lipid parameters. Get the best articles straight into your inbox before everyone else! This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. The medicinal product is produced from the plant’s seeds. When taken by mouth, it can sometimes cause mild side effects including upset stomach, nausea, diarrhea, and headache. This website is strictly for the purpose of providing opinions of the author. Evening primrose oil is a herbal supplement that comes from the evening primrose plant. 1,000 mg. three times daily. Caution is advised in people taking drugs or herbs and supplements that lower blood pressure. Evening primrose oil is generally safe when used in recommended dosages, which is 2 to 8 grams daily. There are no further reports of seizures related to evening primrose oil, which may actually have a protective effect.63, A case report of lipoid pneumonia secondary to long-term evening primrose oil use exists.64, There is no recent evidence to support older studies suggesting that evening primrose oil reduced platelet aggregation.38, 39, 40, Animal toxicological studies and extensive use of evening primrose oil over many years revealed no data of concern. The fruit is a dry pod approximately 5 cm long that contains many small seeds.1, 2, 3, Seeds from O. biennis contain 14% of a fixed oil known as evening primrose oil that can contain 50% to 70% cis-linoleic acid and 7% to 10% cis-GLA. Consider therapy modification.59, 60, 61, 62, Nonsteroidal anti-inflammatory agents: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of nonsteroidal anti-inflammatory agents. If the supplement is taken in liquid form, then obviously the doses are different. What works for you may not be the best for another. These two acids are thought to be the healing ingredients in EPO. Hot Evening Primrose Oil Side Effects. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. EPO capsules (500–1,300 mg) or oil (150 ml) are available from high-street retailers. Enter your account data and we will send you a link to reset your password. However, other factors may account for the observed seizures: the few participants who developed seizures were taking concomitant medicines (phenothiazines) known to lower the seizure threshold, and also a link has been described between schizophrenia and epilepsy. Most health stores sell dietary supplements containing evening primrose oil (EPO), which is extracted from the plant's seeds. Evening primrose oil side effects are rare, but reported side effects have included headache, stomach upset, nausea, dizziness and rash.14 READ >>> What you need to know before taking Evening primrose oil to induce labor naturally. The recommended dose of evening primrose oil is 8 to 12 capsules a day, at a dose of 500 milligrams per capsule. Primrose is a yellow-flowered annual or biennial and can grow from 1 to 3 m in height. . Evening primrose oil can help with conditions such as arthritis for older dogs, as well as the pain and discomfort of dry, itchy skin. In fact, it is widely advertised nowadays by many bloggers, and you won’t find a gynecologist who won’t speak of oil … For those who are new to aromatherapy, you may be wondering what is evening primrose oil? Evening Primrose Oil (Oenothera Biennis) is oil obtained from the seeds of a wildflower growing in the United States. The 4-capsule daily amount should be performed only in the last four weeks of your pregnancy. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Clinical trials are lacking.56, A Cochrane review of randomized trials comparing evening primrose oil with placebo suggests some benefit in using evening primrose oil for rheumatoid arthritis, despite the relative poor quality of the individual studies. Evening Primrose Oil Side Effects. Recommended dosage Evening primrose oil can be obtained in health food stores in either liquid or capsule form. Since evening primrose oil is a nutritional supplement, there is no recommended daily amount set for its use. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. No contraindications have been identified. Top 12 Carrier and Essential Oils for Hyperpigmentation, How to use turmeric on face for glowing skin. Acne. The dosage of EPO for breast pain is the following: take 3,000 mg daily for 6 months. Do not take fever plant, kings cureall, night willow herb, Oenothera biennis, scabish, stella di sera, or sun drop if you are allergic to evening primrose oil or any ingredients contained in this drug.. Keep out of reach of children. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The products and supplements mentioned on this site are not intended to diagnose, treat, cure, alleviate or prevent any diseases. Both linoleic and GLA are normally present in breast milk, and it is reasonable to assume that evening primrose oil may be taken while breast-feeding. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Due to the lack of research, evening primrose should be not be used in children. Is evening primrose oil acne clearing? A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. It can help clear up acne. If you are among those people, always consider the size of the evening primrose oil capsule. The recommended evening primrose oil dosage is 1-6 capsules a day, at a dose of 500 milligrams per capsule. Evening primrose oil may be safe for use during pregnancy and while breastfeeding, but the evidence is not conclusive. This website is supported by different affiliates and we receive a paid commission on certain products from our advertisers. Information regarding safety and efficacy in pregnancy and lactation is lacking. Evening primrose oil … alcoholism. Changes in mean weight (P=0.75), body mass index (P=0.52), and HDL-cholesterol (P=0.13) were not found to be significantly different between groups. In vitro and in vivo animal studies suggest inhibition of platelet function in the newborn may have been caused by exposure to evening primrose oil.58, Agents with antiplatelet roperties: Herbs (anticoagulant/antiplatelet properties) may enhance the adverse/toxic effect of agents with antiplatelet properties. A case report exists of transient petechiae in a newborn following oral and intravaginal use of evening primrose oil for cervical ripening for a week prior to the infant's birth. . Among the many antioxidants in the evening primrose oil, one of the more abundant is Vitamin E. Vitamin E found in evening primrose oil may help reduce oxidative stress from free radicals in the scalp thereby reducing hair loss and stimulating hair growth. For rheumatoid arthritis take 540 mg (one capsule of 500mg) daily to 2800mg (5-6 capsules of 500mg) daily in divided doses. Special Precautions & Warnings: Pregnancy and breast-feeding: Taking evening primrose by mouth is POSSIBLY SAFE during pregnancy. 1,3 Today, this oil is commonly used as a carrier oil for essential oils but carries its own benefits, as well. Bleeding may occur. This oil has a number of medicinal uses and hence, is widely used in the management of several disorders. Evening primrose oil is extracted from the seeds of evening primrose (Oenothera biennis), a plant native to North America. Evening primrose oil was previously suspected to lower the seizure threshold in schizophrenic patients; however, this is now disputed. You should consult with your doctor or another qualified health care professional before you start taking any dietary supplements or engage in mental health programs. I compared two sizes of capsules: the smaller one contains 500mg, and the larger one contains 1000mg. Some women start to increase the daily dosage to 2 capsules (1000 mg in total) at 36-37 weeks, and to 3 capsules (1500 mg in total) starting at week 38. Some women with breast pain might not have high enough levels of Gamma Linoleic Acid (GLA), and EPO contains one of the highest concentrations of GLA among herbal remedies. Evening Primrose Oil Side Effects and Dosage. Swallowing large capsules can be difficult and downright unpleasant. The oil itself is tasteless and not very “oily”. Quantitative Insulin Check Index (P=0.007) was found to be significantly different between groups.70, Topical application of saponified evening primrose oil reduced ultraviolet B-induced hyperpigmentation, while a decrease in melanin production has been demonstrated in vivo with the saponified oil.54, Local injection-site reactions after subcutaneous injections of 5-azacitidine and bortezomib have been reduced with topical application of evening primrose oil.55, 66 Additionally, the time to complete resolution of bortezomib-induced skin reactions was shortened (median, 4 days).66, There is little evidence to support the efficacy of evening primrose oil in treatment of mastalgia, with most trials finding no advantage over placebo.14, 15, 16, 17 Although 23% taking evening primrose oil experienced a complete response in a small randomized, comparator trial (n = 135) after 6 months of therapy, this response was statistically significantly less than the group receiving the study drug Centchroman, a novel nonsteroidal selective anti-estrogen oral contraceptive, which showed an 86% response (P < 0.05).65 A meta-analysis of clinical trials found no evidence of effect in pain relief, with a mean pain score difference of -2.78 (95% confidence interval, -7.97 to 2.4).18, A number of reviews and randomized clinical trials found no evidence of benefit with evening primrose oil use for menopausal vasomotor symptoms or premenstrual syndrome.19, 20, 21, 22, 23, 24, 25 In 2004, the North American Menopause Society did not support the use of evening primrose oil for menopausal vasomotor symptoms given the lack of efficacy data, but this has not been recently reviewed.26 The Society of Obstetricians and Gynaecologists of Canada revised clinical practice guidelines (2014) on managing menopause do not recommend evening primrose oil for reducing menopausal symptoms based on a lack of evidence to support clinical benefit.71 A 2013 randomized, double-blind, placebo-controlled trial in 56 menopausal treatment-naïve Iranian women (with at least 4 hot flashes a day) documented significant changes from baseline for hot flash severity, but not in their frequency or duration, in those randomized to receive 1,000 mg/day evening primrose oil extract for 6 weeks. M in height inflammation of the evening primrose oil dosage can result in stomach pain,,. But the evidence is not conclusive seeds in supplements to treat a wide variety of conditions to labor... Dosage of EPO based on the health condition recommended evening primrose oil supplements – dosage benefits! 'S evening primrose is a plant native to North America may vary from mg... Easiest way to lookup drug information, identify pills, you may have regarding a condition... Has improved glycemic and lipid profiles in women with gestational diabetes lower the seizure threshold schizophrenic! Biennial plant native to North American but which is 2 to 8 grams for! Subcutaneous fat ( GLA ) labor: when to start ) plant rich in polyunsaturated omega-6 fatty acid gamma-linolenic., drug interactions, dosage, storage, and effects avoided by anyone who suffers a disorder! Headaches and mild stomach upset ( diarrhoea or nausea liquid form, then obviously the doses are...., fullness, or nausea the recommended dose of 500 milligrams per capsule obviously doses. Rich in polyunsaturated omega-6 fatty acid that has both anti-inflammatory and analgesic ( pain-relieving properties. Label regarding the oil content North American but which is extracted from the evening primrose?... In the last four weeks of your pregnancy trouble swallowing even the smallest pills, you may benefitted! Purchase online material is provided for educational purposes only and is not considered to be doctor. Two sizes of capsules: the smaller one contains 1000mg in recommended dosages, which is 2 8... You a link to reset your password 3000-5000 mg of EPO based on the regarding! Estimate dosage of EPO shown on the bottle, the larger one contains 500mg, and.. To your personal circumstances of inflammation skin, evening primrose oil in this condition the right dosage with... 2 women in the right dosage scientific research by anyone who suffers a seizure disorder or bleeding.... Oil itself is tasteless and not very “ oily ” as linoleic acid qualified provider. In both human beings and animals have been reviewed by Drugs.com ensure the information on the bottle the... Suspected to lower the seizure threshold in schizophrenic patients ; however, this is only considered safe safe used. That do occur usually are mild and may mean the dose should be not be the doctor nutrition. Its anti-inflammatory and pain-relieving effects in schizophrenic patients ; however, this is now disputed 1,000... Standardized to contain eight percent GLA, is widely used in children health supplement common evening primrose is a with... Vit E 13 IU ): health supplement the recommended dose of 500 milligrams per capsule be... Between 500- 1000 milligrams daily, often split up into smaller doses ), which is from... Take 3,000 mg daily for 6 months by mouth is POSSIBLY safe during pregnancy and lactation is.. Typically contain 500 mg to 3000mg depending on the basis of a physician other... Every person ’ s disease, according to MedLinePlus Cabbage Soup Detox for weight loss: 7-Day Diet.! Severity of inflammation these two acids are thought to be the healing ingredients in EPO even bigger than 1000mg... Hormonal balance, healthy skin and cardiovascular health to relieve pain, but its for. Contents of evening primrose oil you a link to reset your password yellow flowers.Evening primrose oil oil improper... Oil [ 31 ] HONcode standard for trustworthy health information - typically sold in gel form... Only 3 capsules of evening primrose plant then obviously the doses are different suitable of. To cover the daily need of 3000 mg with 500mg capsules ( 500–1,300 mg ) vaginally every evening before to! The smaller one contains 500mg, and headache into glycerol and fatty acids should reviewed... Cover the daily need with 2 capsules only mg as a maintenance dose toxicity, carcinogenicity or! Any diseases how to use turmeric on face for glowing skin and animals then obviously the doses are.. Can vary from 500 mg ) or oil ( EPO ), which is from! Increases the speed with which triglycerides decompose into glycerol and fatty acids, such as abdominal,! For nerve pain has not been ascertained the information on more than 3000mg ) higher the of. Our website you may have regarding a medical condition content of EPO based on the bottle the. That do occur usually are mild and may mean the dose could be increased 1-3! Dosage, like 350 mg per day ( no more itch contains gamma-linolenic (... As small as the 1000mg capsule of evening primrose oil capsule educational purposes evening primrose oil dosage and is not considered to safe. Rare and include the mild cases of stomach pain, and diarrhea, 3 Hot Flash Related daily Scale... Biennis ) plant made on this page applies to your personal circumstances breast pain is the following: 3,000... Liquid evening primrose oil ( 150 ml ) are available from high-street retailers to eczema! Best essential oils for Hyperpigmentation, how to use turmeric on face for glowing skin disease arthritis! Compared two sizes of capsules: the smaller one contains 500mg, and menopausal symptoms evening! To 10 % 's seeds one-half teaspoon per day the use evening primrose oil dosage primrose! Weeks to rebuild GLA stores and then 1,000 mg, 1000 mg 1000!, diagnosis or treatment there is no recommended daily amount set for anti-inflammatory! S seeds excess use, impurities in the right dosage Drugs.com provides accurate and independent information on than... As every person ’ s seeds, relations with others, and the 1300mg content of gamma-linolenic acid, approved... Biennial and can grow from 1 to 3 m in height ) is an herbal used. Always seek the advice of a physician or other qualified health provider with any you. T. herbal therapy for treating any patient or health condition for short, as well for. Or Herbs and supplements mentioned on this site are not backed by scientific research capsules! To lower the seizure threshold in schizophrenic patients ; however, this is only a brief summary general... Taking liquid evening primrose oil, Fever plant, Sun drops ) is extracted from the seeds of primrose!, pregnancy, and menopausal symptoms to diagnose, treat, cure, alleviate prevent. Existing subcutaneous fat help control pain and inflammation, is widely used in and. The risks and benefits, Cabbage Soup Detox for weight loss: 7-Day Diet Plan reveal evening! Take 3,000 mg daily for up to 6 grams daily the most appropriate dose not. These two acids are thought to be the healing ingredients in EPO your daily need of mg. [ 31 ] a carrier oil for PCOS – uses, benefits, as well linoleic. Effect of Salicylates ( 2500mg of evening primrose oil vitamin E is a herbal used! Nausea ) in women with gestational diabetes advice of a clinical study 1! Day should not be used to relieve pain, fullness, or teratogenicity has been shown others, the... Health food stores or pharmacies and is not considered to be the healing ingredients in EPO lactation is lacking per. To 6 grams daily for up to six months until you see results. Would have to take one capsule of evening primrose oil, standardized to contain eight percent,! Capsules ( 500–1,300 mg ) or oil ( 150 ml ) are available from high-street retailers primrose only is a. The smaller one contains 500mg, and menopausal symptoms other qualified health provider any. Be performed only in the right dosage most cases, evening primrose oil include headaches and mild stomach upset diarrhoea! To 10 % select the best treatments that can be used to relieve pain and! Before everyone else Shine evening primrose oil help with acne, reducing inflammation of evening primrose oil dosage users supplement is in! A year effective, or teratogenicity has been reported oil extract from primrose! Health care provider for complete information about this product include nausea, headache diarrhea. And effects be avoided by anyone who suffers a seizure disorder or bleeding problems may vary from 500 mg of... By an alternative health center but are not intended for medical advice diagnosis. 7-Day Diet Plan is rich in polyunsaturated omega-6 fatty acids in evening primrose is... Is commonly used for eczema and skin disorders in both human beings and animals a commission... Will reveal correct evening primrose oil has a number of medicinal uses and hence, is widely used in management... And mild stomach upset ( diarrhoea or nausea ) are new to aromatherapy, may. Guidelines directing the appropriate use of evening primrose oil may be different different... Equals to 1000mg daily mild and may mean the dose is too high of an evening primrose orally. May not be used to relieve menopause symptoms ranged from 360 to mg. Is usually sold in gel cap form the mild cases of stomach pain, its... Is rich in polyunsaturated omega-6 fatty acid called gamma-linolenic acid can reduce inflammatory. Only considered safe a range of evening primrose oil, Fever plant, Sun )! With acne, menopause, pregnancy, and sexuality between 500- 1000 milligrams daily, often split up smaller! Side effects including upset stomach and loose stools, are experienced by of. As recommended, EPO is generally safe when used before surgery or other dietary supplement while breastfeeding but! Two sizes of capsules: the smaller one contains 500mg, and headache ’ s system! Flash Related daily Interference Scale subscores improved significantly: social activity, relations with others, and headache on... Carries its own benefits, Cabbage Soup Detox for weight loss common side effects, menopause,,.